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MASTERS OF SEX is a one-hour drama starring Emmy® and BAFTA Award nominee Michael Sheen and acclaimed actress Lizzy Caplan, who will portray the real-life pioneers of the science of human sexuality, William Masters and Virginia Johnson. The series chronicles the unusual lives, romance, and pop culture trajectory of Masters and Johnson. Their research touched off the sexual revolution and took them from a midwestern teaching hospital in St. Louis to the cover of Time magazine and nearly a dozen appearances on Johnny Carson's couch.