Brian reevaluates his priorities after the bombing of Babylon; Michael continues to recover in the hospital, while a Liberty Avenue vigil for the victims ends in chaos.
The gang fight against Proposition 14, an anti-gay initiative; Babylon gets bombed and Michael nearly loses his life; Justin and Brian contemplate a future together; Mel and Lindsay reunite.
Brian gets testicular cancer; Justin and Michael's comic book takes off; Ted goes to rehab; Emmett dates a pro football player; Melanie and Lindsay separate.
Brian works on the mayoral campaign of a conservative; Michael and Ben adopt an HIV-positive teen; Emmett and Ted's relationship falls apart due to Ted's drug addiction.
Justin gets gay bashed; Michael and Justin start a comic book; Michael starts seeing Ben, and HIV-positive man; Lindsay and Mel get married; Ted starts his own business.
Brian confronts his father's death; Justin falls in love with Brian; Michael dates Dr. David; Ted falls for a Meth addict; Lindsay and Melanie become parents; Emmett tries to go straight.